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Immune complexes

Immune complex

(Science: immunology) Multimolecular antibody antigen complexes that may be soluble or insoluble depending upon their size and whether or not complement is present.

immune complexes can be filtered from plasma in the kidney and the deposition of the complexes gives rise to glomerulonephritis probably because of the trapping of neutrophils via their fc receptors.


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Re: How to knock down a gene?

... specificity, efficacy and lack of non-antisense effects like innate immune stimulation. Getting the oligos into cells is an experimental hurdle ... and new ones are appearing, such as delivery using nanoparticle complexes, virally-mediated transfection or the the Vivo-Morpholinos which ...

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by jonmoulton
Fri Oct 31, 2008 6:46 pm
 
Forum: Genetics
Topic: How to knock down a gene?
Replies: 1
Views: 805

Antibodies

There are two broad categories of immune response: an antibody or serological response, and a cellular response. Different ... cytokines that act to call in other lytic cells; or, finally, antigen-antibody complexes can activate complement, which is similar to the macrophage response in ...

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by blcr11
Mon Jun 11, 2007 4:51 pm
 
Forum: Cell Biology
Topic: Antibodies
Replies: 4
Views: 848

Electron Micrograph of vesicles...

... I would be willing to call it a mast cell. The mast cell is part of the immune system. It makes things like histamine, cytokines, and proteases and ... are coated with IgE receptors and when stimulated by IgE-antigen complexes, they release the contents of the granules into the surroundings ...

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by blcr11
Sat May 26, 2007 3:19 am
 
Forum: Cell Biology
Topic: Electron Micrograph of vesicles...
Replies: 5
Views: 835

GOLGI WIT WOOO

... For example, plasma B cells, the antibody-secreting cells of the immune system, have prominent Golgi complexes. The Golgi bodies are considered the "post office" of the cell. It handles ...

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by keef
Fri Sep 29, 2006 8:25 am
 
Forum: Cell Biology
Topic: GOLGI WIT WOOO
Replies: 1
Views: 360

Allergies

... and tissue damage involved is caused by responses trigerred by immune complexes. Example: serum sickness, Arthus reaction. Allergies mediated by IgE is known as ...

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by Dr.Stein
Mon Feb 06, 2006 6:32 am
 
Forum: Human Biology
Topic: Allergies
Replies: 3
Views: 512
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