Igm --> immunoglobulin M

(Science: immunology) An immunoglobulin M molecule (970 kD) is built up from five immunoglobulin g type monomers joined together, with the assistance of j chains, to form a cyclic pentamer.

immunoglobulin M binds complement and a single molecule bound to a cell surface can lyse that cell. Immunoglobulin M is usually produced first in an immune response before immunoglobulin g.

The human red cell isoantibodies are immunoglobulin M antibodies. Heavy chain (mu chain) is rather larger than the heavy chains of other immunoglobulins.

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