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Igm

Igm --> immunoglobulin M

(Science: immunology) An immunoglobulin M molecule (970 kD) is built up from five immunoglobulin g type monomers joined together, with the assistance of j chains, to form a cyclic pentamer.

immunoglobulin M binds complement and a single molecule bound to a cell surface can lyse that cell. Immunoglobulin M is usually produced first in an immune response before immunoglobulin g.

The human red cell isoantibodies are immunoglobulin M antibodies. Heavy chain (mu chain) is rather larger than the heavy chains of other immunoglobulins.


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Re: Serum IgM cannot activate the complement?

b is correct.

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by preechaedu
Sat Jun 23, 2012 11:15 am
 
Forum: Molecular Biology
Topic: Serum IgM cannot activate the complement?
Replies: 1
Views: 1623

I need help with these questions?

... FOR THE TETANUS TOXIN WOULD PROBABLY BE MOST ABUNDANT IN THE BLODD PLASMA OF A PERSON WHO WAS VACCINATED AGAINST TETANUS 2 YEARS AGO? A. IGA B. IGM C.IGD D. IGG E. IGE WHICH OF THE FOLLLOWING ANTIBODY TYPES CAN BE FOUND IN THE BODY AS DIMER MOLECULE? A. IGD B. IGE C. IGM D. IGA E. IGG WHICH ...

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by chinee
Thu May 10, 2012 11:36 pm
 
Forum: Microbiology
Topic: I need help with these questions?
Replies: 2
Views: 1688

Blood donors and receipients

... are the universal donors because no antibodies can bind to them. However they can only receive other O-type because their plasma contains IgM antigens for both A and B receptors and will quickly kill them off.

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by Babybel56
Sat Apr 23, 2011 7:36 pm
 
Forum: Human Biology
Topic: Blood donors and receipients
Replies: 3
Views: 2723

sperm protein sp17

has anyone done icc for sperm protein sp17? can i use IgM antibodies for ICC? any help is appreciated! thanks

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by Natalya2
Sat Nov 27, 2010 12:42 am
 
Forum: Cell Biology
Topic: sperm protein sp17
Replies: 0
Views: 573

Re: Cytokine - Receptor concepts

... isotype switching we can have different inmunoglobulins that acts in the humoral response. Exist different types of inmunoglobulins, for example: IgM ( wich acts in the complement activation), IgG and it subclasses ( acts in Fc receptor-dependent phagocyte responses, complement activation, neonatal ...

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by marla
Tue Jun 01, 2010 9:08 pm
 
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
Replies: 7
Views: 14563
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