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Hydroxymethylglutaryl coa reductases

(Science: enzyme) in the biosynthesis of cholesterol, these enzymes catalyze the reduction of one of the carboxyl groups of beta-hydroxy, beta-methylglutaryl coa to yield mevalonic acid.4 requires nadp, EC 1.1.1.88 requires nad.

chemical name: (S)-Mevalonate:NAD_ oxidoreductase (coa-acylating)

registry number: EC 1.1.1.88