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Hydrolase

Definition

noun, plural: hydrolases

An enzyme that speeds up the process of hydrolysis.


Supplement

In biochemistry, a hydrolase is an enzyme that speeds up the hydrolysis of proteins, starch, fats, nucleic acids, and other complex biomolecules.

For instance, hydrolases act on the following reaction:

A–B + H2O → A–OH + B–H

Hydrolases are classified as EC 3 (according to the EC number classification of enzymes). Hydrolases can be further classified into various subclasses based on the bonds they act upon, such as nucleases for the hydrolysis of nucleic acids, proteases for proteins, etc.


Word origin: hydrolysis: Gk, comb. form of hýdōr, water + -ase, suffix for names of enzymes.

Synonym: hydrolyst, hydrolytic enzyme.
See also: hydrolysis.


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Re: How much ATP a person consumes...?

Well, some glycoside hydrolase would break the bond - It would probably couple ATP hydrolysis or NADH/FADH hydrolyis and use a positive magnesium ion catalyst. I'd have to find out more info and do a Gibbs on that one. I have no idea ...

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by billyfisher100
Mon Mar 26, 2012 5:54 pm
 
Forum: Cell Biology
Topic: How much ATP a person consumes...?
Replies: 16
Views: 17104

Enzymes

... by bond, made by release of water. So, when you want to break these big molecule, you add water to the previously mentioned bond and this does hydrolase in general. It hydrolyses any bond. Amylase hydrolyse glycosidic bond in carbs, pepsin hydrolyses peptide bond in polypeptides. Look to the ...

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by JackBean
Thu Feb 25, 2010 7:20 pm
 
Forum: Molecular Biology
Topic: Enzymes
Replies: 16
Views: 16348

bifunctional proteins

... Or from my area, there is a LOG (lonely guy) gene, which is assigned as lysine decarboxylase @ RAP database, but they found, it has phosphoribosyl hydrolase activity. Do you know some such genes? Thanks

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by JackBean
Tue Nov 03, 2009 11:19 am
 
Forum: Molecular Biology
Topic: bifunctional proteins
Replies: 4
Views: 4115

Cellulose-Glycogen

beta-(1->4)-cellulose hydrolase ?

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by victor
Wed Jan 24, 2007 9:31 am
 
Forum: Cell Biology
Topic: Cellulose-Glycogen
Replies: 11
Views: 11484

Which fats are easiest to digest and why?

... there's a systematic name (or code) for enzymes :D Example, we can divide enzymes into 6 classes which are: 1. Oxidoreductase 2. Transferase 3. Hydrolase 4. Lyase 5. Isomerase 6. Ligase Each of these classes have their own subclasses classified according with each group involved with the enzymes. ...

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by victor
Mon Jan 08, 2007 6:22 am
 
Forum: Cell Biology
Topic: Which fats are easiest to digest and why?
Replies: 18
Views: 17105
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