(Science: chemical) a thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including oedema, hypertension, diabetes insipidus, and hypoparathyroidism.
Pharmacological action: antihypertensive agents, diuretics, thiazide.
chemical name: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide