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Hydatiform mole

(Science: radiology) trophoblastic proliferation with avascularity of chorionic villi, marked oedema and enlargement of chorionic villi, severe eclampsia prior to 24 weeks, 1st trimester bleeding, abnormal elevation of beta-hCG, passing grapelike vesicles per vagina, uterus large for dates (50%), hyperechoic intrauterine tissue interspersed with numerous punctate hypoechoic areas (hydropic villi), in 25% atypical appearance: large hyperechoic areas (blood clots) and areas of cystic degeneration; resembles incomplete abortion, thick hyperechoic rim around central anechoic zone, bilateral theca lutein cysts (18-37%) see also: gestational trophoblastic disease, hydatiform mole: types