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Hup gene

Hup gene

(Science: molecular biology) human equivalents of the pax genes.


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Re: Gene cloning question

Hi RNAse is nothing but Ribonuclease which actually cleaves a phosphodiester bond between any two ribonucleotides and also degrades RNA into smaller components which is mostly helpful in prokaryotic processes and play a important role in many biological processes.

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by vidya790
Wed Sep 16, 2009 9:22 am
 
Forum: Molecular Biology
Topic: Gene cloning question
Replies: 12
Views: 1516

A gene mutation = knockdown or knockout

Where a gene is altered to lose its function, this is a knockout. Where a gene is altered to decrease its expression, this is a knockdown. Knockdown is also used to describe RNA-level manipulations to decrease gene expression, ...

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by jonmoulton
Mon Sep 14, 2009 7:52 pm
 
Forum: Genetics
Topic: A gene mutation = knockdown or knockout
Replies: 2
Views: 53

How to do gene mutation on an adult ?

Antisense can modify gene expression at the RNA level, making cells that temporarily behave as mutants. However, as the antisense activity decreases with time then normal gene expression resumes. http://en.wikipedia.org/wiki/Antisense_therapy ...

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by jonmoulton
Mon Sep 14, 2009 7:49 pm
 
Forum: Genetics
Topic: How to do gene mutation on an adult ?
Replies: 1
Views: 41

Re: Problems with gene knockdown

An alternative is using antisense to knock down the gene expression. I work for Gene Tools, a company making Morpholino antisense oligos for researchers. Morpholinos can be designed to block translation of mRNA or to modify splicing of pre-mRNA. They ...

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by jonmoulton
Mon Sep 14, 2009 7:45 pm
 
Forum: Molecular Biology
Topic: Problems with gene knockdown
Replies: 1
Views: 87

How to do gene mutation on an adult ?

How to do gene mutation on an adult ? :roll: :roll: :roll: :roll:

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by steelcat
Sun Sep 13, 2009 3:29 am
 
Forum: Genetics
Topic: How to do gene mutation on an adult ?
Replies: 1
Views: 41
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