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Hsp90

Hsp90

(Science: molecular biology) Widely distributed group of conserved heat-shock proteins of average weight 90 kd. Exact function unknown, but are found associated with steroid hormone receptors and tyrosine kinase oncogene products. May also bind actin and tubulin.


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Folding of the insulin molecule

... of course don’t forget chaperones-proteins that help other complex proteins to fold propperly. Mutation of some chaperons can be lethal-eg HSP90 . Cheers!

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by zami'87.
Fri Jul 08, 2005 12:10 pm
 
Forum: Molecular Biology
Topic: Folding of the insulin molecule
Replies: 4
Views: 5104

Re: protein folding

... ribosomes have that function ...so does that mean that most of mutations in genes for chaperones wouldn't be lethal? And I read that mutation for hsp90 would be lethal in early embrionic stage.... Now do you know some diseases related to non functional chaperones? And if someone has idea about ...

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by zami'87.
Tue May 31, 2005 4:15 pm
 
Forum: Molecular Biology
Topic: protein folding
Replies: 1
Views: 1676


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