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Dictionary » H » Homozygous

Homozygous

Definition

adjective

(1) Of, or pertaining to an individual (or a condition in a cell or an organism) containing two copies of the same allele for a particular trait located at similar positions (loci) on paired chromosomes (see homologous chromosomes).

(2) Having two identical alleles that code for the same trait.


Supplement

A ‘homozygous’ organism for a particular trait is described to possess either a pair of dominant alleles (e.g. AA) or a pair of recessive alleles (e.g. aa).


Word origin: G. ‘homo’ meaning ‘same’ + zygous, which pertains to a zygote.

Related forms: homozygosity (noun).
Related phrases: homozygous recessive, homozygous dominant.

Compare: heterozygous.
See also: allele.


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Results from our forum


mutation-selection balance

... recessive alleles). If the allele is not lethal in homozygotes, then q=√(μ/s), where s is again the selection coefficient for those who have a homozygous affected genotype. N.B. √ is square root in case it's not visible. What I don't get is why are the formulas different. For a dominant lethal ...

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by Monco
Mon Mar 04, 2013 10:41 pm
 
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 51

Knockout mice

If one parent is a wild-type mouse and the other is a homozygous knockout mouse, their offspring will be heterozygous at the knockout gene. The mouse will likely produce the protein from the wild-type copy of the gene, but depending on how the gene ...

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by jonmoulton
Tue Feb 05, 2013 5:29 pm
 
Forum: Genetics
Topic: Knockout mice
Replies: 5
Views: 647

Re: Genetics problems

1. a. Given a plant was heterozygous for pod shape and homozygous recessive for plant size b. do you know Punnett square? c. the same as above d. the same as above and above above, just combined 2. Pure breeding means they are homozygous (thus all progeny ...

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by JackBean
Fri Jan 18, 2013 9:09 am
 
Forum: Genetics
Topic: Genetics problems
Replies: 1
Views: 426

Genetics problems

... by a one gene – two allele system with tall size being completely dominant to dwarf size. Given a plant was heterozygous for pod shape and homozygous recessive for plant size: a. What is the phenotype of this plant? b. If this plant was crossed to a dihybrid (heterozygote), what would be ...

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by jamesandrew
Fri Jan 18, 2013 7:20 am
 
Forum: Genetics
Topic: Genetics problems
Replies: 1
Views: 426

Re: Muscular dystrophy inheritance question

... the AAAAAAA the sequence is spliced to different sequences depending on the allele? Why, though, would the male show alternative splicing if he is homozygous? I've clearly not worked out this problem correctly. As you learn more about this one, please post it here.

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by jonmoulton
Thu Jan 10, 2013 3:59 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 1044
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