Dictionary » H » Homozygote



noun, plural: homozygotes

A nucleus, cell or organism where the alleles for a particular gene on each chromosome are identical.


Homozygotes are true breeding organisms since the trait in question can be held constant as they produce the same phenotypic result.

Word origin: Greek ‘homo’ meaning ‘same’ + zygote.
Related forms: homozygous (adjective)

Compare: heterozygote
See also: zygosity

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Re: Knockout mice

... confuses me is that if this is the case, then what's the difference between knock-out and knock-down mice?" The difference is whether the homozygote is expressing some of the gene product. If there is some of the protein made, the mouse is a knock-down and not a knock-out. Watch out for ...

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by jonmoulton
Wed Feb 06, 2013 3:51 pm
Forum: Genetics
Topic: Knockout mice
Replies: 5
Views: 5578

Re: Muscular dystrophy inheritance question

... two different sequences for the female (due to the N position, which shows two traces) and one sequence for the male. It appears the male is a homozygote and the female is heterozygous (at least over the sequence given in the lower traces). The female might have a splice site mutation, as the ...

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by jonmoulton
Thu Jan 10, 2013 3:59 pm
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 7353

Need help in an assignment

... doctor published her answers and according to her the answer is 4-autosome dominant which appears only in males. that means the first male must be homozygote recessive and the first female must hetrozygote, but as we can see she isn't a carrier. So if my doctor is right, could it be that the female ...

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by dreamtim
Sun Sep 09, 2012 4:05 pm
Forum: Genetics
Topic: Need help in an assignment
Replies: 17
Views: 14393

Gene Linkage Problems

... that that rat was heterozygous for both traits. The linked genes on that unknown heterozygote would be R| |b C| |s When this is mated with the b-s homozygote 50% would be R-C/b-s (red/curly) and 50 % would be b-s/b-s (black straight). Which is result listed. One type of cross-over chromosome would ...

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by RLBallantyne
Sun Jan 22, 2012 8:07 pm
Forum: Genetics
Topic: Gene Linkage Problems
Replies: 1
Views: 2997

Punnett Square Question

... this case. What I thought was, since my prof said that the 7 F1 offspring (4 black:3 pink) was a 1:1 ratio (crossing a heterozygote black with a homozygote recessive pink), then perhaps the 9 F2 offspring (6 black:3 pink) is supposed to represent a 3:1 ratio? (crossing 2 F1 heterozygote blacks ...

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by NiceOnTheIce
Fri Jan 14, 2011 2:43 am
Forum: Genetics
Topic: Punnett Square Question
Replies: 5
Views: 2567
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