Dictionary » H » Homozygote

Homozygote

Definition

noun, plural: homozygotes

A nucleus, cell or organism where the alleles for a particular gene on each chromosome are identical.


Supplement

Homozygotes are true breeding organisms since the trait in question can be held constant as they produce the same phenotypic result.


Word origin: Greek ‘homo’ meaning ‘same’ + zygote.
Related forms: homozygous (adjective)

Compare: heterozygote
See also: zygosity


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Re: Knockout mice

... confuses me is that if this is the case, then what's the difference between knock-out and knock-down mice?" The difference is whether the homozygote is expressing some of the gene product. If there is some of the protein made, the mouse is a knock-down and not a knock-out. Watch out for ...

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by jonmoulton
Wed Feb 06, 2013 3:51 pm
 
Forum: Genetics
Topic: Knockout mice
Replies: 5
Views: 4453

Re: Muscular dystrophy inheritance question

... two different sequences for the female (due to the N position, which shows two traces) and one sequence for the male. It appears the male is a homozygote and the female is heterozygous (at least over the sequence given in the lower traces). The female might have a splice site mutation, as the ...

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by jonmoulton
Thu Jan 10, 2013 3:59 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 5683

Need help in an assignment

... doctor published her answers and according to her the answer is 4-autosome dominant which appears only in males. that means the first male must be homozygote recessive and the first female must hetrozygote, but as we can see she isn't a carrier. So if my doctor is right, could it be that the female ...

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by dreamtim
Sun Sep 09, 2012 4:05 pm
 
Forum: Genetics
Topic: Need help in an assignment
Replies: 17
Views: 11476

Gene Linkage Problems

... that that rat was heterozygous for both traits. The linked genes on that unknown heterozygote would be R| |b C| |s When this is mated with the b-s homozygote 50% would be R-C/b-s (red/curly) and 50 % would be b-s/b-s (black straight). Which is result listed. One type of cross-over chromosome would ...

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by RLBallantyne
Sun Jan 22, 2012 8:07 pm
 
Forum: Genetics
Topic: Gene Linkage Problems
Replies: 1
Views: 2661

Punnett Square Question

... this case. What I thought was, since my prof said that the 7 F1 offspring (4 black:3 pink) was a 1:1 ratio (crossing a heterozygote black with a homozygote recessive pink), then perhaps the 9 F2 offspring (6 black:3 pink) is supposed to represent a 3:1 ratio? (crossing 2 F1 heterozygote blacks ...

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by NiceOnTheIce
Fri Jan 14, 2011 2:43 am
 
Forum: Genetics
Topic: Punnett Square Question
Replies: 5
Views: 2358
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