Dictionary » H » Homeodomain

Homeodomain

Definition

noun, plural: homeodomains

A protein domain consisting of 60 amino acid residues encoded for by a homeobox. It is commonly found in transcription factors. Its function is to bind to specific sequence on a gene, which either activates or represses gene expression.


Supplement

Homeodomain folds induce cell differentiation by initiating the cascades of coregulated genes required to produce individual tissues and organs. They are exclusive in multicellular, organ-forming eukaryotes.


See also: homeobox.


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How old is the ancestral protein likely to be.

... HEHBOX6 57.8 2e-07 gi|119370800|sp|Q1KKR6|HXD4B_FUGRU Homeobox protein Hox-D4b >... 57.8 2e-07 gi|396779|emb|CAA52159.1| sex combs reduced homeodomain prote... 57.8 2e-07 gi|18858849|ref|NP_571219.1| homeo box C5a [Danio rerio] >gi|... 57.8 2e-07 gi|123295378|emb|CAM16416.1| homeo box ...

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by go&go
Wed Mar 07, 2007 4:11 am
 
Forum: Molecular Biology
Topic: How old is the ancestral protein likely to be.
Replies: 2
Views: 2219

distinction b/t homeotic genes and master genes?

The homeobox is a DNA sequence which codes for a particular DNA binding domain called the homeodomain. I have also found out that the definition of a homeotic gene is not that it contains a homeobox as I previously thought. It is actually based in the genes function. ...

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by herb386
Tue Jul 11, 2006 10:00 am
 
Forum: Genetics
Topic: distinction b/t homeotic genes and master genes?
Replies: 6
Views: 4538

distinction b/t homeotic genes and master genes?

wow...so much terms I am not familiar with... can someone perhaps explain what a homeobox and homeodomain are?

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by student12
Mon Jul 10, 2006 11:00 am
 
Forum: Genetics
Topic: distinction b/t homeotic genes and master genes?
Replies: 6
Views: 4538

distinction b/t homeotic genes and master genes?

... turn on determines the way of the sexdetermination. --> homeotic genes are indeed as already said genes with a homeobox encoding for the homeodomain. These genes yield homeotic transformations in drosophila.

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by sdekivit
Thu Jul 06, 2006 7:17 pm
 
Forum: Genetics
Topic: distinction b/t homeotic genes and master genes?
Replies: 6
Views: 4538

distinction b/t homeotic genes and master genes?

... a series of other genes involved in some process then you would call it a master gene. If you are talking about a master gene which contains a homeodomain sequence then you would call it a homeotic gene. Master genes can control any process, like SRY which controls the sex of the organism in ...

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by herb386
Tue Jul 04, 2006 11:38 am
 
Forum: Genetics
Topic: distinction b/t homeotic genes and master genes?
Replies: 6
Views: 4538
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