Dictionary » H » Homeobox



noun, plural: homeoboxes

DNA sequence (of about 180 base pairs) contained in a gene (e.g. hox gene), and code for a protein domain (of about 60 amino acids) that is highly conserved, and can bind to DNA to control gene expression.


An example of homeobox is the one found in homeotic genes. In fact, this is where its name was derived from since its occurrence was first discovered in homeotic gene. But not all homeoboxes are homeotic, or causing homeosis. The term homeobox refers only to the sequence in the gene.

Word origin: homeo(tic gene) + box.

Related term: homeobox gene

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