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Hiv envelope

Hiv envelope protein gp120

external envelope protein of the human immunodeficiency virus which is encoded by the hiv env gene. It has a molecular weight of 120,000 kd and contains numerous glycosylation sites. Gp120 binds to cells expressing cd4 cell-surface antigens, most notably t4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of cd4 and is at least partly responsible for the cytopathic effect of hiv.

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Vaccine for HIV

... viral diseases by priming the adaptive immunity to recognize the viral envelope proteins have failed in the case of HIV-1. Some have stated that an HIV vaccine may not be possible without significant theoretical ...

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by suzidoc8
Mon Jul 23, 2012 2:47 pm
Forum: Microbiology
Topic: Vaccine for HIV
Replies: 1
Views: 7627

Viral budding

... retroviruses with the assistance of reverse transcriptase. Taking the HIV virus as an example, upon completion of viral proteins being synthesised ... cell, the mature virus can then leave via budding - forming a viral envelope. I know this means that the capsid is enveloped within a portion ...

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by Poggie
Wed Nov 30, 2011 7:36 pm
Forum: Microbiology
Topic: Viral budding
Replies: 1
Views: 1765

Question about viruses (particularly hiv)

... mechanisms. It requires permanent changes to the proteins, lipid envelope or the nucleic acids of the virus, thus rendering the viral particle ... material into them - these can be used as gene delivery vectors. HIV is pretty typical as a virus: it is quite fragile and gets easily destroyed ...

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by biohazard
Tue Oct 26, 2010 11:21 am
Forum: Microbiology
Topic: Question about viruses (particularly hiv)
Replies: 25
Views: 51449

Invasion of a host cell by a DNA virus

... either icosahedral or helical, is surrounded by a loose membranous envelope. The envelope is roughly spherical but makes varying shapes because ... This can only be done with viruses that contain an envelope such as HIV or influenza. By the way of endocytosis in which the virus tricks the ...

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by littlexsparrow
Wed Sep 23, 2009 7:14 pm
Forum: Microbiology
Topic: Invasion of a host cell by a DNA virus
Replies: 1
Views: 13843

HIV Exposure to air

... in air because it is not their physiological environment. HIV spreads via transfer of body fluids, so it hasn't even had a real reason ... conformation and the lipid membrane degrades. Since HIV requires its envelope in order to be infectous, this also destroys the infective virus. ...

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by biohazard
Mon Dec 08, 2008 8:14 am
Forum: Microbiology
Topic: HIV Exposure to air
Replies: 7
Views: 36847
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