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Dictionary » H » Hill constant

Hill constant

Hill constant --> hill coefficient

a measure of cooperativity in a binding process. A hill coefficient of 1 indicates independent binding, a value of greater than 1 shows positive cooperativity binding of one ligand facilitates binding of subsequent ligands at other sites on the multimeric receptor complex. Worked out originally for the binding of oxygen to haemoglobin (hill coefficient of 2.8).


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