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Hfr cell

Definition

noun

A bacterial cell that possesses the F factor integrated into the bacterial genome, hence, when it conjugates with another bacterium, it attempts to transfer a copy of the F factor as well as a portion of or the entire chromosome to the recipient bacterium.


Supplement

Hfr stands for high frequency of recombination first described by the population geneticist, Luca Cavalli-Sforza. The bacterial cell that acquires F plasmid and incorporates to the bacterial chromosome through crossover, the cell is now designated as Hfr.

During conjugation, the Hfr bacterium would attempt to transfer its entire DNA to the F-bacterium. However, since the mating bridge is structurally fragile the genetic transfer is often incomplete. Hence, the recipient bacterium may only receive a portion of, and rarely the entire, bacterial genome of the donor Hfr bacterium.


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Results from our forum


Re:

... They do have recombination, obviously, which is why the bacterial cell becomes an Hfr, conjugating into F- instead of F+. This does not make any sense. What does correcting ...

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by ChesneMD
Thu Nov 17, 2011 4:13 am
 
Forum: Evolution
Topic: Viral-induced evolution
Replies: 6
Views: 5434

Viral-induced evolution

... They do have recombination, obviously, which is why the bacterial cell becomes an Hfr, conjugating into F- instead of F+. This does not make any sense. What does correcting ...

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by canalon
Thu Nov 17, 2011 3:34 am
 
Forum: Evolution
Topic: Viral-induced evolution
Replies: 6
Views: 5434

Re:

... They do have recombination, obviously, which is why the bacterial cell becomes an Hfr, conjugating into F- instead of F+. My hypothesis is not based on bad research, and your ...

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by ChesneMD
Wed Nov 16, 2011 9:16 pm
 
Forum: Evolution
Topic: Viral-induced evolution
Replies: 6
Views: 5434

Conjugation Mapping Basics

My question is regarding bacterial conjugation between Hfr and F -ve. The transfer of DNA from Hfr begins at oriT. The gene closest to oriT on the donor chromosome enters the recepient cell, followed by successive genes on the donor chromosome. The frequency of a particular ...

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by cytochromeP
Sat Oct 29, 2005 11:53 am
 
Forum: Genetics
Topic: Conjugation Mapping Basics
Replies: 0
Views: 2477


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