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Hfr bacterium


noun, plural: Hfr bacteria

A bacterium that possesses the F factor integrated into the bacterial genome, hence, when it conjugates with another bacterium, it attempts to transfer a copy of the F factor as well as a portion of or the entire chromosome to the recipient bacterium.


Hfr stands for high frequency of recombination first described by the population geneticist, Luca Cavalli-Sforza. The bacterial cell that acquires F plasmid and incorporates to the bacterial chromosome through crossover, the cell is now designated as Hfr.

During conjugation, the Hfr bacterium would attempt to transfer its entire DNA to the F-bacterium. However, since the mating bridge is structurally fragile the genetic transfer is often incomplete. Hence, the recipient bacterium may only receive a portion of, and rarely the entire, bacterial genome of the donor Hfr bacterium.

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Compare (with other bacteria in terms of F factor):

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Need help on a few genetics questions please.

... does it impact our understand of the nature and function of genes? The bacterium Salmonella typhimurium forms Hfr strains at a much lower frequency than it’s sister species Escherichia coli. Based upon ...

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by Anonymous
Sun Mar 23, 2008 11:22 pm
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