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Dictionary » H » Heterozygous

Heterozygous

Definition

adjective

(1) Of, or pertaining to an individual (or a condition in a cell or an organism) containing two different alleles for a particular trait.

(2) Having dissimilar alleles that code for the same gene or trait.


Supplement

Example: a zygote having one dominant allele and one recessive allele, i.e. Aa, for a particular trait.


Word origin: G. héteros the other of two, other, different + zygous, which pertains to a zygote.

Related forms: heterozygosity (noun).
Related phrases: heterozygous recessive, heterozygous dominant.

Compare: homozygous.
See also: allele.


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Results from our forum


Pedigree Analysis

1. Cannot be x-linked recessive: in order to have an affected female progeny, you need to have heterozygous carrier mother AND father. That means that father would be affected too (single X chromosome). 2. Thus, it's an autosomal (see above) recessive (since neither parent ...

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by Cat
Sun Apr 28, 2013 3:09 pm
 
Forum: Genetics
Topic: Pedigree Analysis
Replies: 1
Views: 660

Pedigree Analysis

... are affected. 2. Affected sons are usually born to unaffected mothers; thus, the trait skips generations. 3. Approximately half of a carrier (heterozygous) mother’s sons are affected. 4. Never passed from father to son. 5. All daughters of affected fathers are carriers. Also I am unsure if ...

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by chapsticks4
Tue Feb 26, 2013 7:06 pm
 
Forum: Genetics
Topic: Pedigree Analysis
Replies: 1
Views: 660

Conditional knockout mouse

... mouse where my gene of interest is floxed. When I cross this mouse line with Tamoxifen inducible Cre line, CAGGCre-ERTM, I get mice with with heterozygous Cre and floxed gene of interest. The experimental plan was to isolate myoblasts from these mice and induce Cre in cell culture by addition ...

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by aji01
Wed Feb 20, 2013 11:25 am
 
Forum: Genetics
Topic: Conditional knockout mouse
Replies: 1
Views: 571

Knockout mice

If one parent is a wild-type mouse and the other is a homozygous knockout mouse, their offspring will be heterozygous at the knockout gene. The mouse will likely produce the protein from the wild-type copy of the gene, but depending on how the gene is regulated it is likely ...

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by jonmoulton
Tue Feb 05, 2013 5:29 pm
 
Forum: Genetics
Topic: Knockout mice
Replies: 5
Views: 1593

Knockout mice

Can someone please explain how it is possible to have a heterozygous knock out mouse? If a gene is "knocked-out," how can the mouse be heterozygous for the gene? Will the mouse still produce express this "knocked-out" gene? Thanks ...

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by cassieconte
Tue Feb 05, 2013 4:54 pm
 
Forum: Genetics
Topic: Knockout mice
Replies: 5
Views: 1593
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