Heterochromatic

... 6*]. In mammals, it is the female which dosage compensates, by silencing most of the genes on one of the two chromosomes via the formation of a heterochromatic Barr body (reviwed in [7, 8]). In this review, we focus on how the cell distinguishes the X from the autosomes as the correct target ...

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... is piggyBac. The site of integration of the transgene can influence gene expression due to the effects of nearby transcription enhancers or silent heterochromatic regions. Position effects can be minimized by flanking a transgene with insulator elements. The scs/scs' and gypsy insulators from Drosophila ...

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... extracting DNA you'll be extracting every ounce of genomic DNA from the cell. This includes all gene-DNA, exons, introns, flanking regions, all heterochromatic/non-coding/junk DNA from every single chromosome as well as mitochondrial and plasmid DNA contained in the cells that your'e lysing. ...

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