Dictionary » H » Hepatocyte

Hepatocyte

Definition

noun, plural: hepatocytes

Any of the large, polygonal-shaped cells in the liver.


Supplement

Hepatocytes are the major functional component of the liver. They make up 70-80% of the mass of the liver.

They are parenchyma cells arranged in plates that anastomose with one another. Most of them have a single nucleus although binucleate cells are also not uncommon. They also have abundant rough and smooth endoplasmic reticulum, as well as stacks of Golgi membrane, which are necessary for their function.

They perform various functions such as synthesis of proteins and lipids for secretion, storage and transformation of carbohydrates (e.g. glycogen into glucose), synthesis of cholesterol, bile salts and phospholipids, and detoxification, modification and excretion of exogenous and endogenous substances.


Word origin: Greek hépat-, s. of hêpar liver + New Latin -cyta, from Greek kutos, hollow vessel.

Synonym: liver cell.
See also: liver.


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Results from our forum


Is there a cell line that can synthesize ascorbic acid?

i would agree, since it is the hepatocyte that carries out the metabolic functions in the liver.

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by MrMistery
Thu Jan 03, 2008 1:34 pm
 
Forum: Zoology Discussion
Topic: Is there a cell line that can synthesize ascorbic acid?
Replies: 3
Views: 2214

Is there a cell line that can synthesize ascorbic acid?

... (rat, mouse, etc.) can synthesize Vit. C in the liver for themselves. I has not even got a chance to check which cell type does the job (probably hepatocyte?).

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by hanhan2008
Mon Dec 24, 2007 2:44 am
 
Forum: Zoology Discussion
Topic: Is there a cell line that can synthesize ascorbic acid?
Replies: 3
Views: 2214

The Fiber Disease

... factor, platelet-derived growth factor, vascular endothelial cell-derived growth factor, epidermal growth factor, insulin-like growth factor, hepatocyte growth factor, and fragments and combinations thereof. 7. The implant of claim 1, wherein the growth factor is autologous. 8. The implant ...

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by Nadas Moksha
Fri Nov 17, 2006 12:59 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5559953

Steatosis with rare Glycogenated Hepatocyte

I just had a liver biopsy and the diagnosis reads as follows "Mild nonspecific large droplet steatosis with rare Glycogenated Hepatocyte nuclei. Can anyone please tell me what that means??? :?

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by d daley
Sun Aug 20, 2006 4:48 am
 
Forum: Human Biology
Topic: Steatosis with rare Glycogenated Hepatocyte
Replies: 5
Views: 3149

Glycoprotein

a few of roles of glycoproteins: - cell to cell binding. A hepatocyte will never bind to any other cell than another hepatocyte for example. - deposits of cations. usually glycoproteins are sulfatated or acetylated - protection of the cell from enzymes. ...

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by MrMistery
Fri Feb 24, 2006 6:28 pm
 
Forum: Cell Biology
Topic: Glycoprotein
Replies: 3
Views: 2177
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