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Helicases

Helicase --> dna helicase

(Science: enzyme molecular biology) a prokaryote enzyme that uses the hydrolysis of atp to unwind the dna helix at the replication fork, to allow the resulting single strands to be copied. Two molecules of atp are required for each nucleotide pair of the duplex.


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the true definition of replication complex

... I found a statement that replication complexes help catalyze reactions of replication. While in the other part of the textbook, it said that DNA helicases and Single-strand binding proteins are involved in replication of DNAs as well. Both of the descriptions have already confused me. Are DNA ...

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by flyingfree
Sat Jan 09, 2010 9:14 am
 
Forum: Molecular Biology
Topic: the true definition of replication complex
Replies: 0
Views: 912

Re: Question for experts: Helicases

Thanks kolean

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by AFJ
Wed Jul 08, 2009 2:13 am
 
Forum: Molecular Biology
Topic: Question for experts: Helicases
Replies: 4
Views: 4559

Question for experts: Helicases

Here is a link to a free access on PubMed about several different kinds of helicases: http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18329872 In a human/eukaryotic cell, there are multiple origins of DNA replication. Helicases are ...

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by kolean
Sat Jul 04, 2009 11:03 pm
 
Forum: Molecular Biology
Topic: Question for experts: Helicases
Replies: 4
Views: 4559

Re: Question for experts: Helicases

From here Helicase works in both directions opening the DNA molecule. How? Does it split in two, or are there more helicases that enter into the picture. The only thing I can find is that it makes a fork in the DNA and a really cheap animation. Maybe they don't really know in detail. ...

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by AFJ
Sat Jul 04, 2009 8:47 pm
 
Forum: Molecular Biology
Topic: Question for experts: Helicases
Replies: 4
Views: 4559

Question for experts: Helicases

Can anyone explain to me how the helicase process in strand separation is possible as far as time? Are there several helicases taking each a portion of the DNA, or does one start at one end and split the entire strand? If the latter is the case, how does it separate 3 billion nucleotides ...

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by AFJ
Sat Jul 04, 2009 2:34 pm
 
Forum: Molecular Biology
Topic: Question for experts: Helicases
Replies: 4
Views: 4559
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