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Haplotypes

Haplotypes

The genetic Constitution of individuals with respect to one member of a pair of allelic genes; sets of single alleles or closely linked genes that tend to be inherited together, such as those of the major histocompatibility complex; portions of phenotypes determined by genes located on one of a pair of chromosomes.


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I have got some BIG issues! forgive the long post

... an increased risk for development of many autoimmune diseases, are known to often be inherited together in an extended haplotype O. The extended haplotypes could be evolutionary conserved and are often refereed to as ancestral haplotypes. The allelic diversity of MHC genes is, in contrast to ...

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by saddy51
Sun Jan 04, 2015 10:39 am
 
Forum: Genetics
Topic: I have got some BIG issues! forgive the long post
Replies: 1
Views: 1784

Phylogeny and haplotype mapping programs

Hello! I have previously used MGEA for my phylogenetic analysis and draw evolutionary trees. In this project, I have a certain number of haplotypes, I have to calculate distances. What is the most common, acceptable, free to use program for haplotype mapping? What is the most accepted programs ...

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by sevdakara
Tue Jul 15, 2014 8:29 pm
 
Forum: Ecology
Topic: Phylogeny and haplotype mapping programs
Replies: 0
Views: 1022

Microsatellites

Which criteria should I follow to select a couple of microsatellite markers for an haplotype determination study? Between haplotypes and within haplotypes.

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by MirrisRq
Fri May 17, 2013 6:11 pm
 
Forum: Genetics
Topic: Microsatellites
Replies: 0
Views: 829

How to draw a blot from a RFLP physical map?

Hi, all you need to understant is, whether there is the restriction site or is not. That tells you the table of haplotypes.Thus haplotype A has both EcoRI sites 3 and 4, while in haplotype the site 4 was mutated and thus the enzyme is not able to cut the DNA there, thus the DNA ...

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by JackBean
Thu Nov 24, 2011 1:07 pm
 
Forum: Genetics
Topic: How to draw a blot from a RFLP physical map?
Replies: 7
Views: 3860

How to draw a blot from a RFLP physical map?

... the blot to a labeled probe. Draw a picture of what the blot will look like when the DNA comes from individuals homozygous for the following haplotypes: the probe is on sites 2,3,4 the distance between site 1 and 2 is 1.5kb site 2 and 3 is 2 kb sites 3 and 4 is 1kb and sites 4 and 5 is 4 ...

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by ssimon10
Wed Nov 23, 2011 2:43 pm
 
Forum: Genetics
Topic: How to draw a blot from a RFLP physical map?
Replies: 7
Views: 3860
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