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Haplotypes

Haplotypes

The genetic Constitution of individuals with respect to one member of a pair of allelic genes; sets of single alleles or closely linked genes that tend to be inherited together, such as those of the major histocompatibility complex; portions of phenotypes determined by genes located on one of a pair of chromosomes.


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Can you use mtDNA to...

The limits of using mtDNA for determining who is more closely related to whom is that there are a limited number of haplotypes present in a population compared to the total number of indivduals in the population. Two individuals might have the same mtDNA sequence, which means that ...

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by wbla3335
Tue Apr 28, 2009 12:45 pm
 
Forum: Genetics
Topic: Can you use mtDNA to...
Replies: 12
Views: 1482

Can you use mtDNA to...

... how closely related they are - within limits. Barring new mutations, mtDNA within any species will exist in a limited number of different haplotypes (mtDNA is haploid). That is, there are a limited number of different sequences of the mtDNAs within a species. All individuals differ in ...

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by wbla3335
Sat Apr 25, 2009 8:06 am
 
Forum: Genetics
Topic: Can you use mtDNA to...
Replies: 12
Views: 1482

Intragenic and Interlocus Conversion Rates, Haplotypes

... L in gene 3 on the maternal chromosome have the AHL haplotype. Maybe the paternal chromosome has SNP R in gene 2, so its haplotype would be ARL. Haplotypes don't have to be the entire chromosome, though. They are just the collection of the different polymorphisms at different loci that are all ...

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by wbla3335
Sat Jan 31, 2009 9:36 am
 
Forum: Molecular Biology
Topic: Intragenic and Interlocus Conversion Rates, Haplotypes
Replies: 1
Views: 357

Intragenic and Interlocus Conversion Rates, Haplotypes

I'm reading a paper on the pseudogenization of certain genes through gene conversion, but the paper contains some terminology that I'm a little new to, and neither the internet or my book seem to give a very good explanation of it. So could anyone give me a general idea about what intragenic and int...

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by ConorFlynn
Fri Jan 30, 2009 8:37 pm
 
Forum: Molecular Biology
Topic: Intragenic and Interlocus Conversion Rates, Haplotypes
Replies: 1
Views: 357

Re: Brain size=IQ level theory (Blacks vs Whites & Asians)

... positive selection in the lineage leading to Homo sapiens (Zhang, 2003; Evans et al, 2005). Within modern humans a group of closely related haplotypes, known as ‘haplogroup D’ arose from a single copy at this locus (Evans, 2006). Globally, D alleles are young and first appeared about 37,000 ...

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by bluecafe669
Tue Apr 15, 2008 12:50 am
 
Forum: Human Biology
Topic: Brain size=IQ level theory (Blacks vs Whites & Asians)
Replies: 18
Views: 12481


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