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HLA

HLA: human leukocyte antigen. A group of genes in the human major Histocampatibility complex (MHC).


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What is gluten?

... people can process gluten without problems and it is a normal component of human nutrition. In some people with certain human leukocyte antigens (HLA) and predisposing genetics gluten may bind on the HLA molecules and initiate an autoimmune-like response that is the source of the celiac disease. ...

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by biohazard
Tue Oct 09, 2012 7:42 am
 
Forum: Human Biology
Topic: What is gluten?
Replies: 2
Views: 494

Re: Gluten-free and Vaccines

... undergo vesicular trafficking into the cytoplasmic Golgi (35). By analogy with the current understanding of how gliadin peptides are acquired by HLA-DQ2 via a tTGase-mediated pathway (3), we hypothesized that these Pro-Gln-rich segments of both pertactin and the phosphatase are likely to be high-affinity ...

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by tmerezko
Tue Jun 22, 2010 6:08 pm
 
Forum: General Discussion
Topic: Gluten-free and Vaccines
Replies: 7
Views: 12314

Primers for HLA typing

Hello, for HLA typing you can use sequence specific primers from Invitrogen or any other company. But the sequence of these primers is a "business secret" therefore you have to order the whole kit if you want them. I ...

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by marko1985
Sun Feb 22, 2009 7:35 pm
 
Forum: Molecular Biology
Topic: Primers for HLA typing
Replies: 2
Views: 1931

Renal transplant - HLA antibodies

... immunology case studies with one on a 40 year old mother needing a renal transplant but she has an acute rejection about 5 days later and anti-HLA antibodies are found in her blood. Can anyone help me by explaining why she has developed these antibodies so soon, are the results below so different ...

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by uhna
Mon Dec 08, 2008 9:10 pm
 
Forum: Cell Biology
Topic: Renal transplant - HLA antibodies
Replies: 0
Views: 1177

how stem cell tech make people live longer

... (e.g. a person who has had their own stem cells destroyed by chemotherapy or radiotherapy when treating cancer) own stem cells are replaced by HLA-matched cells from a donor, after which the stem cells establish themselves to the bone marrow of the patient and restart blood cell production. ...

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by biohazard
Fri Oct 17, 2008 6:04 am
 
Forum: Genetics
Topic: how stem cell tech make people live longer
Replies: 1
Views: 2420
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