Granuloma

... provides an ideal environment for rods to multiply logarithmically. These macrophages are then activated and they aggregate to form the granuloma. A compact palisade, of many cells thick of macrophages around the focus of infection. They may then fuse to form giant multinucleate cells. ...

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Well I think the cause in TB is that areas infected by bacteria are surrounded by lymphocytes. They tend to clump around the area which forms a granuloma.

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Can anyone explain to me why you get granulomas forumed in TB and in sarcoidosis? Thanks

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... bodies (“kunkers”) on the limbs, chest, and abdomen (58, 59). Dogs and horses may also present with intestinal obstruction due to pythium granuloma in the duodenum or jejunum (51, 56). The organism may be isolated from fresh clinical material seeded onto mycologic medium, such as Sabouraud's ...

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THE ROLE OF CHEMICAL MEDIATORS IN THE INFLAMMATORY RESPONSE INDUCED BY FOREIGN BODIES: COMPARISON WITH THE SCHISTOSOME EGG GRANULOMA Both divinyl benzene copolymer (plastic) beads and schistosome eggs produce inflammatory reactions after intravenous deposition into the lung of a mouse. ...

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