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Granulation tissue

Definition

noun

The connective tissue forming on major wounds during tissue repair. It consists largely of new blood vessels, fibroblasts, immune cells, endothelial cells, myofibroblasts, and a provisional extracellular matrix.


Supplement

During the proliferative phase of wound healing, the granulation tissue appears red or pink in color due to angiogenesis. It is also moist, soft and granular in appearance. It replaces the initial fibrin clot on wound. An excess of granulation tissue is termed proud flesh.


See also: granulation, proud flesh.


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The Fiber Disease

... moisture of the genitalia or eyes, they migrate into and irritate the tissue, which causes a granulomatous reaction. The lesion becomes chronic, ... may kill the larvae. Surgical removal or cauterization of the excessive granulation tissue may be necessary. Treatment with ivermectin (200 µg/kg) ...

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by Skytroll
Thu Jul 06, 2006 4:19 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5478998

For Mr. Hill

... of the nodule was consistent with an infectious process, and tissue was sent for bacterial, fungal, and mycobacterial cultures, including ... resonance imaging highlighted a soft tissue abnormality consistent with granulation tissue. A provisional diagnosis of a foreign body infection with ...

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by C3
Tue Jan 31, 2006 6:59 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5478998

The Fiber Disease

... manipulate multiple host cell signalling pathways. Also: Connective tissue growth factor (CTGF) is a cysteine-rich peptide synthesized and secreted ... in a wound chamber model of fibrosis in rats. CTX also reduced dermal granulation tissue fibroblast population increases induced by TGF-ß in neonatal ...

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by London
Wed Jan 11, 2006 4:34 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5478998


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