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Dictionary » G » Granulation

Granulation

Definition

noun, plural: granulations

(1) The act or process of forming grains or granules, e.g. the granulation of powder and sugar.

(2) The formation of granulation tissue, i.e. the new connective tissue which replaces the initial fibrin clot on wounds.


Supplement

Granulation is the major healing process occurring in second intention healing. Healing takes place from the bottom upward by filling in the dead space with granulation tissue.


Word origin: LL grānulum small grain + L -ātiōn- (s. of -ātiō), equiv. to -ā- s. vowel + -tiōn.

Related terms: granulation tissue.


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The Fiber Disease

... of benefit, and organophosphates applied topically to the abraded surface may kill the larvae. Surgical removal or cauterization of the excessive granulation tissue may be necessary. Treatment with ivermectin (200 µg/kg) has been effective, and although there may be temporary exacerbation of the ...

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by Skytroll
Thu Jul 06, 2006 4:19 pm
 
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For Mr. Hill

... the lesion could not rule out the presence of a foreign body, but magnetic resonance imaging highlighted a soft tissue abnormality consistent with granulation tissue. A provisional diagnosis of a foreign body infection with the possibility of a marine or aquarium-associated microorganism was considered. ...

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by C3
Tue Jan 31, 2006 6:59 pm
 
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The Fiber Disease

... transgene. Both 8-Br-cAMP and CTX blocked TGF-ß-induced collagen deposition in a wound chamber model of fibrosis in rats. CTX also reduced dermal granulation tissue fibroblast population increases induced by TGF-ß in neonatal mice, but not increases induced by CTGF or TGF-ß combined with CTGF. ...

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by London
Wed Jan 11, 2006 4:34 pm
 
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