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Gpi anchor

Gpi anchor

(Science: biochemistry molecular biology) Common modification of the c terminus of membrane attached proteins in which a phosphatidyl inositol moiety is linked through glucosamine and mannose to a phosphoryl ethanolamine residue that is linked to the c terminal amino acid of the protein by its amino group.

Glypiation is the sole means of attachment of such proteins to the membrane. The name comes from the addition of glycosyl phosphatidyl inositol (PI).


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Edman Degradation Problem

... code, but I know that if it is a transmembrane protein it should have a large region containing hydrophobic/nonpolar amino acids so that it can anchor itself into the membrane E) So neither my professor or my book goes over which amino acids can be phosphorylated...but after some research on ...

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by pinkerpikachu
Sun Oct 16, 2011 7:35 pm
 
Forum: Molecular Biology
Topic: Edman Degradation Problem
Replies: 1
Views: 4224

Features of the leading strand synthesis on DNA ends

... some literature I have find a data, describing two mechanisms for this problem - first, that polymerase before the catalytic centre also have an anchor centre, and when it comes close to the extremal end of the template, the enzyme will dissociate from the DNA molecule, leaving the last nucleotides ...

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by carterjer3
Wed Sep 28, 2011 11:56 am
 
Forum: Molecular Biology
Topic: Features of the leading strand synthesis on DNA ends
Replies: 2
Views: 3691

How does phospholipids aid the cell and the rest of the body

thanks man im thinking in the right direction but another fuction of the phospholipid bi-layer is to anchor protein molecules to the cell membrane so they project outwards is there any simple explanation as to why the phospholipid bi-layer can anchor protein molecules together

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by ccBiologist
Thu Sep 15, 2011 5:38 am
 
Forum: Molecular Biology
Topic: How does phospholipids aid the cell and the rest of the body
Replies: 7
Views: 8202

How does phospholipids aid the cell and the rest of the body

... but how does their structure aid the cell membrane or contribute to the cell membrane being semi-permeable ? I read that phospholipids anchor the cell membranes protein how does it do this? Also could anyone give some ways that the structure of phospholipids relates to its function ...

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by ccBiologist
Thu Sep 15, 2011 3:42 am
 
Forum: Molecular Biology
Topic: How does phospholipids aid the cell and the rest of the body
Replies: 7
Views: 8202

Membrane proteins

... like it does actually exists. The protein would be a hollow capsule containing a tethered polymer chain inside, that is released, for example to anchor to a substrate or for recognition purposes. I would be thrilled if someone can point in me the right direction to look for it! Best, Poroto

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by poroto
Wed Mar 09, 2011 12:51 pm
 
Forum: Cell Biology
Topic: Membrane proteins
Replies: 4
Views: 2779
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