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Gpi anchor

Gpi anchor

(Science: biochemistry molecular biology) Common modification of the c terminus of membrane attached proteins in which a phosphatidyl inositol moiety is linked through glucosamine and mannose to a phosphoryl ethanolamine residue that is linked to the c terminal amino acid of the protein by its amino group.

Glypiation is the sole means of attachment of such proteins to the membrane. The name comes from the addition of glycosyl phosphatidyl inositol (PI).


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Re: mannose extraction with methanol/chloroform

... has any other roles in the cell. I know it has another function as a GPI anchor but is anyone aware of any others? cheers

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by spinkster
Thu Apr 24, 2008 2:48 pm
 
Forum: Cell Biology
Topic: mannose extraction with methanol/chloroform
Replies: 2
Views: 2337

PNA

... this shedding is done by a phospholipase which specifically cuts GPI anchor of this protein. But, this may be useful to block a cascade of reactions,; if we add ...

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by abhay
Sat Mar 19, 2005 9:35 pm
 
Forum: Molecular Biology
Topic: PNA
Replies: 19
Views: 11232

PNA

... this shedding is done by a phospholipase which specifically cuts GPI anchor of this protein. But, this may be useful to block a cascade of reactions,; if we add ...

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by abhay
Sat Mar 19, 2005 9:33 pm
 
Forum: Molecular Biology
Topic: PNA
Replies: 19
Views: 11232


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