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Gp120

Gp120

(Science: protein, virology) a glycoprotein from HIV's envelope that binds to the cd4 molecules on cells outside membrane.

free gp120 in the body may be toxic to cells on its own, causing cd4 cell depletion in the immune system through apoptosis and neurological damage leading to aids dementia complex.


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Biology tests

... on biology tests. One question on the test was for example: What is aids? And I answered by writing about the HIV-virus, its functions (including GP120 and that it affects Th-cells and macrophages) and how it affects the body and the immunesystem. However my teacher added that I should had written ...

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by finalfantasy
Tue Jan 07, 2014 4:01 pm
 
Forum: General Discussion
Topic: Biology tests
Replies: 1
Views: 1361

Vaccine for HIV

... The epitopes of the viral envelope are more variable than those of many other viruses. Furthermore, the functionally important epitopes of the gp120 protein are masked by glycosylation, trimerisation and receptor-induced conformational changes making it difficult to block with neutralising ...

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by suzidoc8
Mon Jul 23, 2012 2:47 pm
 
Forum: Microbiology
Topic: Vaccine for HIV
Replies: 1
Views: 7860

Re:

... cell to a Cd4 t cell, and place the CD3 protein on the surface of the CD4 t cell to act as a replacement. This would hopefully make it so that HIV gp120 wouldnt be able to bind to t-cells Perhaps I'm missing something here, but as far as I know both gamma/delta and "normal" alpha/beta ...

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by biohazard
Fri May 28, 2010 12:39 pm
 
Forum: Molecular Biology
Topic: Cluster of Differenciation(CD) replacement... Immunology
Replies: 6
Views: 6383

Cluster of Differenciation(CD) replacement... Immunology

... cell to a Cd4 t cell, and place the CD3 protein on the surface of the CD4 t cell to act as a replacement. This would hopefully make it so that HIV gp120 wouldnt be able to bind to t-cells

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by mortonman1
Thu May 27, 2010 10:24 pm
 
Forum: Molecular Biology
Topic: Cluster of Differenciation(CD) replacement... Immunology
Replies: 6
Views: 6383

Re: HIV Exposure to air

... virus particles inside the human body. Don't understand fully why it is that some molecule cannot be developed with a high affinity to the GP160 (GP120 + GP41) complex that would effectively avoid other receptors on other cells?

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by ENROCK
Mon Nov 16, 2009 1:07 pm
 
Forum: Microbiology
Topic: HIV Exposure to air
Replies: 7
Views: 37183
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