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Glycolysis

Definition

noun

(1) The initial metabolic pathway of cellular respiration in which a series of reactions happening in the cytosol results in the conversion of a monosaccharide, often glucose, into pyruvic acid, and the concomitant production of a relatively small amount of high-energy molecules, such as ATP.

(2) The cellular degradation of the simple sugar, glucose, to yield ATP as an energy source.


Supplement

The most common and well-known type of glycolysis is the Embden-meyerhof pathway, initially explained by Gustav Embden and Otto Meyerhof.

The term can be taken to include alternative pathways, such as the Entner-Doudoroff Pathway.


Word origin: Greek, glykys = sweet, referring to sugar + Iyein = to loosen.

Related forms: glycolytic (adjective).

Synonym: Embden-meyerhof pathway.
See also: Krebs Cycle, cellular respiration.


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Re: Increase in free energy in glycolysis

Increase in free energy just refers to Gibbs free energy. That free energy comes from enthalpy (internal energy) - entropy (chaos). Also expressed as Gibbs Free Energy = Enthalpy - Entropy. The idea is that with each subsequent step of glycoysis there is more chaos and thus the entropy goes up and t...

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by daniel.kurz
Wed Feb 05, 2014 3:03 am
 
Forum: Molecular Biology
Topic: Increase in free energy in glycolysis
Replies: 3
Views: 629

Re:

... they are not interested in partiall pathways (like if half of the pyruvate was degraded before it was stopped due to lack of NAD+ and FAD:) Glycolysis will definitelly take part. Probably also the pyruvate decarboxylation. However, the TCA cycle is questionable, because with 100 molecules ...

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by caters
Mon Feb 03, 2014 4:37 am
 
Forum: Cell Biology
Topic: ATP produced by human cells in an anaerobic chamber. LOST!
Replies: 2
Views: 1656

Increase in free energy in glycolysis

I'm reading about glycolysis in a general biology textbook. It says that in the first 5 steps the free energy increases with each step. Two of those steps are powered by ATP, but the rest are not. In those other steps, how does the ...

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by cadamcross
Sat Feb 01, 2014 2:25 am
 
Forum: Molecular Biology
Topic: Increase in free energy in glycolysis
Replies: 3
Views: 629

Re:

it does not relate to the timing but to the question whether they can run at the same time with glycolysis JackBean I've just had a check at another textbook and you were right! Unlike what I first thought, glycolysis can't take place once glycogenolysis has started because ...

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by Aymeric
Sat Dec 14, 2013 11:51 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 2483

Re:

... question was about that exactly... I know that GNG happens, I just don't know when. but to the question whether they can run at the same time with glycolysis I don't see why not? As long as glucose levels are low... what would stop them from running? The phosphorylase that starts glycogenolysis ...

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by Aymeric
Fri Dec 13, 2013 2:46 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 2483
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