(1) The initial metabolic pathway of cellular respiration in which a series of reactions happening in the cytosol results in the conversion of a monosaccharide, often glucose, into pyruvic acid, and the concomitant production of a relatively small amount of high-energy molecules, such as ATP.
The most common and well-known type of glycolysis is the Embden-meyerhof pathway, initially explained by Gustav Embden and Otto Meyerhof.
The term can be taken to include alternative pathways, such as the Entner-Doudoroff Pathway.
Word origin: Greek, glykys = sweet, referring to sugar + Iyein = to loosen.
Related forms: glycolytic (adjective).