Glycine synthase

Glycine synthase --> glycine cleavage complex

a complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce co2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinaemia.

Synonym: glycine synthase.

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