glycerophosphate shuttle

a mechanism for the transfer of reducing equivalents from the cytosol into the mitochondria; nadh is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (dhap) using FAD; dhap then returns to the cytosol to complete the cycle; found in brain tissue, brown adipose tissue, and white muscle.

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