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Gluconeogenesis

Gluconeogenesis

(Science: biochemistry) synthesis of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. Takes place largely in liver and serves to maintain blood glucose under conditions of starvation or intense exercise.


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Increase in free energy in glycolysis

There is difference between standard Gibbs energy and actual Gibbs energy. The other reactions are close to equilibrium (thus they can be used by gluconeogenesis as well) and only the actual concentrations of the substrates/products determine which way it will go.

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by JackBean
Thu Feb 06, 2014 10:42 am
 
Forum: Molecular Biology
Topic: Increase in free energy in glycolysis
Replies: 3
Views: 2438

When does gluconeogenesis kick in during physical activity?

The article gives a lot of background on general gluconeogenesis, which is why I tagged it. And apparently, enzymes involved in glycogen transformation inhibit gluconeogenesis...or maybe it's intermediate products...

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by Darby
Wed Dec 25, 2013 2:30 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 6273

When does gluconeogenesis kick in during physical activity?

Thanks Darby, but the article is about renal gluconeogenesis, which starts only in prolonged fasting conditions, unlike liver GNG. Yes it is true that glycogen reserves would usually be enough, but that doesn't mean that GNG does not take place ...

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by Aymeric
Fri Dec 20, 2013 6:36 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 6273

Re:

Isn't gluconeogenesis SYNTHESIS of glucose, rather than breakdown of glycogen? Yes, I'm not sure what your point is (?) I know that predators with almost no carb sources do that, but it seems that it would require pretty extreme ...

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by Aymeric
Sat Dec 14, 2013 11:11 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 6273

When does gluconeogenesis kick in during physical activity?

Isn't gluconeogenesis SYNTHESIS of glucose, rather than breakdown of glycogen? I know that predators with almost no carb sources do that, but it seems that it would require pretty extreme conditions to kick in for human...

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by Darby
Sat Dec 14, 2013 10:03 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 6273
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