Methylated genes are acquired at fertilization. As the zygote develops into a fully grown organism, its somatic cells will bear the same methylated genes. At the time that the organism produces its own gametes, the imprinted genes are un-methylated. Nonetheless, genomic imprints would be re-instituted in its genome. The location of gene methylation would depend on the sex of that organism. The new gene imprints would consequently affect the phenotype of the its progeny. The effect would rely upon the sex of that organism transmitting the chromosome containing the methylated gene (i.e. whether it is a female or male parent).