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Dictionary » G » Genetic marker

Genetic marker

Definition

noun, plural: genetic markers

A gene or (a fragment of) DNA sequence having a known location on a chromosome, has an easily identifiable phenotype and whose inheritance pattern can be followed.


Supplement

Genetic markers act as chromosomal landmarks. They are used to trace or identify specific region of a gene (especially one that is associated with an inherited disease) on a chromosome. They are also used to determine a linkage group or a recombination event.


Also called: marker, marker gene, DNA marker.
See also: genetic map.


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linkage disequlibrium, haplotypes, SNPs

... between LD, haplotypes and SNPs. Is that correct? SNPs act as markers, they may be in LD with the susceptibility alleles for a disease. Generally, SNPs together with other genetic variants (like disease alleles) can be inherited in/as haplotypes, which means ...

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by tou
Thu Apr 21, 2011 12:11 am
 
Forum: Genetics
Topic: linkage disequlibrium, haplotypes, SNPs
Replies: 1
Views: 381

Genetic Engineering: Vectors

must? With two markers, you can use more combinations with other vectors, you have higher selection pressure, than with only one marker... What vectors are you reffering to? For what genetic engineering?

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by JackBean
Mon Feb 15, 2010 12:20 pm
 
Forum: Molecular Biology
Topic: Genetic Engineering: Vectors
Replies: 2
Views: 653

T cell differentiation

Well, you almost got it :) RTEs already express CD4 or CD8 marker (all T cells leaving the thymus are "single positive" CD4+ ... monitoring thymic output in both healthy individuals and in patients with genetic or acquired CD4+ T cell immunodeficiencies." (Haines et al. 2009)

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by biohazard
Thu Apr 16, 2009 6:53 pm
 
Forum: Human Biology
Topic: T cell differentiation
Replies: 16
Views: 15729

Re:

Hi It seems that not so many people here interested in Population genetic anyway I have an other question Who know what does effective alleles ... HWE, does this mean that this gene cannot be used as a genetic marker or there is no hope for this Loci to be in Linkage-disequilibrium with ...

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by F4T32008
Sun May 11, 2008 4:23 pm
 
Forum: Genetics
Topic: About Pop. genetic heterozygosity & HWE
Replies: 4
Views: 2696

About Pop. genetic heterozygosity & HWE

... fourth year Zoology science and I am so interested in population genetic and bioinformatics I read a lot of scientific articles in Population ... HWE, does this mean that this gene cannot be used as a genetic marker or there is no hope for this Loci to be in Linkage-disequilibrium ...

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by Proteinic
Tue May 06, 2008 3:41 pm
 
Forum: Genetics
Topic: About Pop. genetic heterozygosity & HWE
Replies: 4
Views: 2696
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