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Gene regulation

Definition

noun

The modulation of any of the stages of gene expression, hence, it encompasses the various systems that control and determine which genes are switched on and off, and when, how long, and to what extent the genes are expressed.


Supplement

Gene regulation may occur in the following stages of gene expression:

Gene regulation of the lac operon of the prokaryotes was the first genetic regulatory mechanism to be elucidated.


Variant: regulation of gene expression

See also: regulator gene.


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Re: translation from DNA

... modern biochemistry. However, I can speculate that much of the regulation of gene expression occurs at the RNA level, with variations in the stability of RNA, translational ...

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by jonmoulton
Mon Sep 29, 2014 3:03 pm
 
Forum: Molecular Biology
Topic: translation from DNA
Replies: 2
Views: 214

Re: Odd mechanism for cancer

... especially in older articles. http://www.infoplease.com/cig/biology/regulation-gene-expression-prokaryotes-eukaryotes.html You should Google operon + interon + cancer, then ...

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by oldfaithful
Thu Jun 26, 2014 12:56 pm
 
Forum: Cell Biology
Topic: Odd mechanism for cancer
Replies: 6
Views: 4272

Re: How Genes/expression Determine Organism Shape

... in birth defects. As to the other aspect of your question - genetic regulation of organism's size: Imagine this: Gene1 = produces growth hormone Gene 1 allele A (which is a variant of this gene) - can make ...

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by Cat
Mon May 20, 2013 1:41 pm
 
Forum: Genetics
Topic: How Genes/expression Determine Organism Shape
Replies: 2
Views: 5341

Problem with the normalization of PCR Ct values

... something like "The expression was observed to be X copies of the gene of interest mRNA / copy of reference gene mRNA" ? Finally if I want to present the data as 2^ΔCt, negative values mean down-regulation and positive values up-regulation? If you could suggest any literature ...

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by Tzia
Wed May 01, 2013 8:48 pm
 
Forum: Molecular Biology
Topic: Problem with the normalization of PCR Ct values
Replies: 5
Views: 4255

Genetic testing: reliability, accuracy, experience?

It is not "the genes" that cause genetic diseases, since most of us contain all the same genes. ... The genes and their expression is often a very complicated process involving many regulation steps and lots of interaction with other genes, so the existence of a bad allele ...

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by biohazard
Mon Apr 15, 2013 8:55 am
 
Forum: Genetics
Topic: Genetic testing: reliability, accuracy, experience?
Replies: 3
Views: 4103
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