Dictionary » G » Gene mutation

Gene mutation

Definition

noun, plural: gene mutations

A genetic change at the level of the genes; a change in the nitrogenous base sequences.


Supplement

Gene mutations may occur spontaneously during replication (called spontaneous mutations) or they may be induced through mutagens (called induced mutations).

Gene mutations based on the mechanism that caused it are as follows:


Word origin: gene + mutation

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Results from our forum


mutation-selection balance

... that results in death before the person can reproduce. This is termed a genetic lethal mutation because, even though the individual might survive for some time, he or she contributes ...

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by Monco
Mon Mar 04, 2013 10:41 pm
 
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 113

p53 question

... ). The wrap53 gene is produces mRNA that is antisense to p53 mRNA(see http:// http://www.sciencedaily.com/releases/2009/02/090227072646.htm) ... these two proteins could regulate cellular levels of p53? How could a mutation in both wrap 53 and PHF20 lead to cancer in a cell? THANK YOU SO ...

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by qwerter
Wed Feb 13, 2013 2:07 am
 
Forum: Cell Biology
Topic: p53 question
Replies: 1
Views: 300

Human Pathology 'Multiple-Choice Questions'

... prior to the hemorrhage. 6. A XY subject with the loss-of-function mutation in the 5-reductase gene would have which of the following at birth? a. uterus and scrotum b. vas deferens and ...

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by ScrimmSphere
Mon Feb 04, 2013 11:03 am
 
Forum: Human Biology
Topic: Human Pathology 'Multiple-Choice Questions'
Replies: 1
Views: 336

Pyrosequencing

Hello, I would like to sequence a gene region with a couple of mutation hot spots nearby each other, and I have a few questions. I guess after PCR amplification of the ...

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by kk
Wed Jan 23, 2013 3:08 pm
 
Forum: Molecular Biology
Topic: Pyrosequencing
Replies: 2
Views: 422

Re: Muscular dystrophy inheritance question

... therefore it is not Duchenne muscular dystrophy (DMD) and is not a mutation of the dystrophin gene. Thanks, I had missed that. The upper sequences look identical, while the lower sequences ...

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by jonmoulton
Thu Jan 10, 2013 3:59 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 1134
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