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Gene activation

Gene activation

The process of activation of a gene so that it is expressed at a particular time. This process is crucial in growth and development.


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What is A ADAM GENE ??????/????

Well there is an ADAM gene family, they are a family of extracellular metalloproteases that cleave the extracellular ... genes in that family. they are involved (at least) in the first steps in the activation of the Notch Receptor. I remember the ADAM proteases have also been connected ...

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by MrMistery
Sun May 03, 2009 5:44 pm
 
Forum: General Discussion
Topic: What is A ADAM GENE ??????/????
Replies: 1
Views: 199

Questions

... a recessive autosomal disorder. What are the causes that lead to the activation of this gene only after 30 years of age? Looking forward to the replies. Thanks in advance!

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by prateeiik
Tue Jan 20, 2009 8:23 am
 
Forum: Human Biology
Topic: Questions
Replies: 3
Views: 459

Re: splicing MO vs translation MO

... the hypothesis the the phenotype is due to knockdown of the targeted gene and not an off-target RNA. Only if the off-target RNA had sites where ... the RT-PCR product. SplicePossibilities.gif Here is a paper describing activation of a cryptic site. In this case, the cryptic site was in the exon, ...

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by jonmoulton
Wed Aug 20, 2008 4:57 pm
 
Forum: Molecular Biology
Topic: splicing MO vs translation MO
Replies: 14
Views: 2210

splicing MO vs translation MO

Thanks Jon, Activation of p53 by MO only causes necrosis in brain, it won't affect CE phenotype. Actually, ... of MO can cause CE phenotype, this may be caused by knocking down some other unknown gene rather than p53. Still, I dont know wheher the CE phenotype I observed with ATG MO ...

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by rose9999
Wed Aug 20, 2008 1:19 am
 
Forum: Molecular Biology
Topic: splicing MO vs translation MO
Replies: 14
Views: 2210

5 questions without answers...!

... two yrs of work. Thanks again for any help. Here we go: 1. A fusion gene for a membrane protein Y is fused to GFP. After transfection, where ... endothelial and monocyte cells in regards to the mechanism of receptor activation for VEGFR? I cannot find any trace of information about this. ...

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by djm129129
Wed Aug 06, 2008 3:05 pm
 
Forum: Molecular Biology
Topic: 5 questions without answers...!
Replies: 2
Views: 750
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