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Gelatinase

Definition

noun, plural: gelatinases

(1) Pepsin B derived from pepsinogen B. It is similar to pepsin A but with more restricted specificity on B chain of insulin than pepsin A.

(2) A proteolytic enzyme in organisms that confer the ability to hydrolyze gelatin into smaller peptides or chains of amino acids.

(3) A group of matrix metalloproteinases, specifically MMP2 and MMP9, with gelatin-binding region in the catalytic domain.


Supplement

Gelatinases can be found in many bacteria that can hydrolyze gelatin. Examples of organisms that produce gelatinases are Pseudomonas aeruginosa and Serratia marcescens.

In humans, MMP2 and MMP9 form a group of gelatinases capable of degrading type IV collagen and gelatin. They are involved in the normal proteolysis of extracellular matrix such as in embryonic development, tissue remodeling, and reproduction.


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Microbiology help in identifying Gram + rod for my unknown

... is seen to be much larger. Spores= + capsules= - motility= ? seemed to be nonmotile in the wet mount, and slight red formation towards top of gelatinase, but I thought that was only due to introduction of oxygen. I dont know. Acid fast stains were shown to form chains with rods and spores ...

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by ccapelouto838
Thu May 03, 2012 5:21 am
 
Forum: Microbiology
Topic: Microbiology help in identifying Gram + rod for my unknown
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Views: 8114

Help with unkown

... s (believed, hard to see the shape with microscope) Opt 37C Motility believed - not 100% Facultative Anerobe . Ran FTM, Catalase, and Oxidase test Gelatinase - Carbohydrate fermentation Glucose + Lac - ran skim milk and lactose test mannitol + maltose - sucrose - Methyl Red + Vouges - Proskauer ...

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by bruserboy1
Thu Apr 05, 2012 3:48 pm
 
Forum: Microbiology
Topic: Help with unkown
Replies: 0
Views: 1086

Help identifying unknown bacteria

We couldnt run additional tests but if we could have I would have ran a gelatinase or nitrate reduction test to differentiate between the two organisms.

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by anthony7
Tue Apr 03, 2012 2:03 am
 
Forum: Microbiology
Topic: Help identifying unknown bacteria
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Unknown Bacillus

... bacteria. I have identified it as a Bacillus, but that's about it. Streptobaclli, Gram +, some endospores present. Scores on the following tests: Gelatinase producing neg Strach Hydrolysis pos Lipid hydrolysis neg Casein hydrolysis (produces caesase) pos Carbohydrate Fermentation Lactose pos w/o ...

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by Ania
Mon Oct 08, 2007 4:38 pm
 
Forum: Microbiology
Topic: help identifying unknown bacteria
Replies: 6
Views: 99603


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