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Gdp-ribosyl cyclase

Gdp-ribosyl cyclase

(Science: enzyme) catalyses the conversion of ngd_ (the guanine analog of nad) to cyclic GDP-ribose

registry number: EC 3.2.2.-


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cAMP 2nd Messenger Pathway and Experiments

I really like your explanation of B. I would think that it would be probable that the cyc- cells (which are only believed to have no adenylyl cyclase present) may actually have adenylyl cyclase present, or that there is a different class of the adenylate cyclase that can act in the place of the ...

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by mkay28
Wed Sep 25, 2013 3:14 pm
 
Forum: Cell Biology
Topic: cAMP 2nd Messenger Pathway and Experiments
Replies: 2
Views: 2257

cAMP 2nd Messenger Pathway and Experiments

... cell line is obtained. The cell line is thought to not have adenylyl cyclase within it, and is called cyc-. You need to test that it doesn't have ... hormone receptor. It interacts with GTP regulatory site to prohibit the GDP from binding. If ATP or GTP were eliminated from the reaction, it would ...

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by mkay28
Tue Sep 24, 2013 10:43 pm
 
Forum: Cell Biology
Topic: cAMP 2nd Messenger Pathway and Experiments
Replies: 2
Views: 2257

cAMP as second messenger in GPCR signal transduction

... cGMP and Calcium ions. And no, GPCRs do relay the message solely through cAMP, they can, as I remember, activate phospholipase C and guanynyl cyclase as well.

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by MrMistery
Sun Feb 15, 2009 4:13 pm
 
Forum: Cell Biology
Topic: cAMP as second messenger in GPCR signal transduction
Replies: 3
Views: 4976

epinephrine

... has a direct effect on glycolysis other than to stimulate the production of glucose from glycogen. Beta adrenergic stimulation activates adenyl cyclase which increases the levels of cAMP, which activates cAMP-dependent kinase, that phosphorylates (activates) phosphorylase kinase, which in turn ...

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by blcr11
Fri Jul 20, 2007 1:53 pm
 
Forum: Cell Biology
Topic: epinephrine
Replies: 3
Views: 3819

LIF, HGF and G alpha s

... Now i dont know how LIF + HGF causes self-renewal; I don't know how the LIF pathway predominates. When Gas is on; this cause adenylate cyclase to be active and causes the production of cAMP I know that cAMP activates PKA which inhibits MAPK, so I dont know how you still get differentiation ...

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by kocho
Fri Dec 01, 2006 8:17 am
 
Forum: Cell Biology
Topic: LIF, HGF and G alpha s
Replies: 0
Views: 1746
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