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Gap protein

Gap protein --> GTPase activating protein

(Science: molecular biology) Originally purified as a 125 kd protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state.

gap may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (pdgf R, egf R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to gap. Gap has both SH2 and SH3 domains. Another example is sar 1 (from yeast).

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plasmodesm and gap junction

The answer I found is that plant cell walls are not permeable to big proteins (more than 30-60 kDa), so they must be passed by plasmodesmata (with ... for protein transportation. So an animal cell necessarily doesn't have gap junction. But I'm not sure. Is it right? Any idea would be appreciated.

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by mnatashgaran
Mon Apr 01, 2013 7:46 pm
Forum: Cell Biology
Topic: plasmodesm and gap junction
Replies: 1
Views: 1906

Re: 'Evolution'-the most retarded myth ever.

... We see then that the mutation reduces the specificity of the ribosome protein and that means a loss of genetic information. ... Rather than saying ... Christian progessive creationists, old earth creationists, gap creationists or theistic evolutionists would disagree with young earth ...

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by Forests
Sun Oct 07, 2012 7:55 pm
Forum: Evolution
Topic: 'Evolution'-the most retarded myth ever.
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Views: 8600

Re: Android app for Pairwise Protein Alignment

... own amino acid sequences for alignment or... if you just enter PDBID or protein NCBI accession ID, the app automatically fetches the protein sequence from the database and aligns them. Other features of the app: Gap penalties: Open, Affine and Extension penalties Substitution matrices: ...

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by deeptakverma
Wed Aug 22, 2012 3:50 pm
Forum: Bioinformatics
Topic: Android app for Pairwise Protein Alignment
Replies: 7
Views: 6779

Prevalence of gene

... that have already been assigned) this takes you to page with: SELECTED PROTEIN SIMILARITIES Comparison of cluster transcripts with RefSeq proteins. ... you different answers - ) and you can adjust the stringency using the GAP-penalties section. You can generate a lifetimes work on one gene alone ...

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by merv
Sun Oct 02, 2011 9:01 pm
Forum: Bioinformatics
Topic: Prevalence of gene
Replies: 8
Views: 9360

Re: Height

... then use some sort of prosthesis or support to allow bone to fill that gap. It's a laborous and expensive process, and not even very successful. ... "solid bone" and do not grow any length. Excessive intake of proteins doesn't make one taller, but can make one fatter. If combined to ...

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by biohazard
Thu Mar 27, 2008 6:54 pm
Forum: Human Biology
Topic: Height
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