(Science: pathology) death of tissue, usually in considerable mass and generally associated with loss of vascular (nutritive) supply and followed by bacterial invasion and putrefaction.

Compare: necrosis.

Origin: L. Gangraena, gr. Gangraina = an eating sore The localized death of living cells (as from infection or the interruption of blood supply).Undergo necrosis; the tissue around the wound necrosed.Necrotic tissue; a mortified or gangrenous part or mass.A condition where tissue begins to decay due to bad circulation in that area, making it easy pray for infection to set in via bacteria.

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