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Gak cyclin g-associated kinase

GAK, cyclin G-associated kinase

(Science: chemical) Has a ser/thr protein kinase-like catalytic domain at the n-terminal; contains a tensin/auxilin-like domain; genbank d38560

Synonym: gak protein

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cdc25 and tyrosin-15

... a phosphatase which dephosphorylates the tyrosine 15 residue of the cyclin-dependent kinase (Cdk). Dephosphorylation of tyrosine-15 of Cdk activates its kinase activity. You introduced ...

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by jb0378
Wed Jul 29, 2009 10:18 pm
Forum: Cell Biology
Topic: cdc25 and tyrosin-15
Replies: 1
Views: 97

Difference b/n cdc5 and cdk5

... of names--which is entirely possible--both CDC5 and CDK5 are kinases. The CDC names derive from Leland Hartwell's studies on the genetics ... are related to polo-like kinases. CDK, on the other hand, is short for cyclin-dependent kinase. CDK5 is one of many kinases regulated via complex ...

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by blcr11
Wed Jul 18, 2007 2:22 pm
Forum: Molecular Biology
Topic: Difference b/n cdc5 and cdk5
Replies: 3
Views: 569

Recent Nature papers

... Cheng, DiPinho, Sharpless, Scadden. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature. 2006:443, pp421-426. (Can't get the INK4a to be superscripted; ...

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by G-Do
Mon Oct 09, 2006 3:14 pm
Forum: Genetics
Topic: Stem Cells & Telemore lengths & Mitochondrial DNA
Replies: 3
Views: 797


TGF-B does downregulate cyclin A by increasing gene expression of p21, a cdk activating kinase inhibitor

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by sdekivit
Sun Dec 11, 2005 10:49 am
Forum: General Discussion
Replies: 1
Views: 566


Acitve MPF is a kinase that phosphorylates Lamin proteins of the nuclear lamina, and promotes nuclear envelope ... This is not one of my favourite areas of the cell cycle. I wish they'ed just call it Cyclin B/Cdk1. You know MPF isnt even mentioned in the massive textbook Molecular Biology ...

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by Chris4
Fri Apr 29, 2005 10:54 am
Forum: Cell Biology
Topic: BCECF
Replies: 1
Views: 1232

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