Edit page | Page history | Printable version

Furin

(Science: protein) subtilisin like eukaryotic endopeptidase with substrate specificity for consensus sequence arg X Lys/Arg arg at the cleavage site.

furin is known to activate the haemagglutinin of fowl plague virus and will cleave the hiv envolope glycoprotein (gp160) into two portions, gp120 and gp41, a necessary step in making the virus fusion competent.