Dictionary » F » Furin

Furin

Furin

(Science: protein) subtilisin like eukaryotic endopeptidase with substrate specificity for consensus sequence arg X Lys/Arg arg at the cleavage site.

furin is known to activate the haemagglutinin of fowl plague virus and will cleave the hiv envolope glycoprotein (gp160) into two portions, gp120 and gp41, a necessary step in making the virus fusion competent.


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified 21:16, 3 October 2005. This page has been accessed 1,880 times. 
What links here | Related changes | Permanent link