Dictionary » F » Fumarate



(Science: biochemistry) a dicarboxylic acid intermediate in the tricarboxylic acid cycle. Can be derived from aspartate, phenylalanine and tyrosine for input to the krebs Cycle.

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Re: Number of water molecules produced by cellular respiration

... cis Aconitate into D-isocitrate. Net water gain zero. One in one out. Later in the Kreb's cycle a single water molecule is consumed in converting fumarate into malate. This gives you one water molecule consumed per acetyl Co A or two consumed per glucose catabolized just within the Kreb's. These ...

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by thornthor
Sun Nov 03, 2013 5:48 pm
Forum: Cell Biology
Topic: Number of water molecules produced by cellular respiration
Replies: 8
Views: 16993

Re: TCA inhibitor

... coenzyme Q process, a totally different substrate by then, formed after many catabolism processes.So, when the new oxygen atom is bonded to form fumarate by fumarase, the structure changes in the cycle, so as it is a muxh similar structure to succinate and only one step after, compared to the ...

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by billyfisher100
Fri Jan 20, 2012 1:21 am
Forum: Cell Biology
Topic: TCA inhibitor
Replies: 3
Views: 8133


fumarate and glutamate have no rate-limiting step, because they are just chemicals :roll:

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by JackBean
Mon Oct 04, 2010 10:28 am
Forum: Cell Biology
Topic: Chemistry
Replies: 1
Views: 1019


... am suppose to determine malonate's site of action in the citric acid cycle. The results tell that malonate is first acted upon by succinate, then fumarate, malate, and lastly pyruvate where it can be converted to acetyl-CoA which feeds the acetyl group into the citric acid cycle. The enzyme that ...

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by adaffara
Fri Oct 01, 2010 11:44 pm
Forum: Molecular Biology
Topic: Malonate
Replies: 3
Views: 6327

Electron Transport Chain

... Citrate to cis-Aconitate, and then use 1 H2O (-1) to make Isocitrate. [EDIT -- cut out, see below] Finally, you use one more H2O (-1) going from Fumarate to Malate. Add all those together and you net -2 H2O per Kreb's cycle (i.e. per pyruvate cum acetyl-CoA), and that happens twice per Glucose, ...

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by mamoru
Mon Mar 15, 2010 12:47 pm
Forum: Molecular Biology
Topic: Electron Transport Chain
Replies: 3
Views: 6153
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