1. (Science: anatomy) Generally a small sac or vesicle.

2. (Science: botany) a kind of fruit formed from a single carpel, that splits to release its seeds.

3. (Science: dermatology) a hair follicle, an invagination of the epidermis into the dermis surrounding the hair root.

4. (Science: gynaecology, physiology) An ovarian follicle, an oocyte surrounded by one or more layers of granulosa cells. As the ovarian follicle develops a cavity forms and it is then termed a graafian follicle. Any small spherical group of cells containing a cavity.A small sac-like cavity.

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