Dictionary » F » Fold

Fold

Fold

1. A ridge or margin apparently formed by the doubling back of a lamina.

See: plica.

2. In the embryo, a transient elevation or reduplication of tissue in the form of a lamina.


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Mitochondrial DNA

Just a short question. I always thought "the mutational rate of mtDNA is ten fold higher than that of nuclear DNA" and now I read "Although much more slowly, mitochondrial DNA does mutate". Which one is true then? Maybe some references from an ...

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by kk
Thu Aug 22, 2013 2:25 pm
 
Forum: Cell Biology
Topic: Mitochondrial DNA
Replies: 17
Views: 8052

protein fractionation

... just have to try different approaches and detect both your protein (enzymatic activity?, blotting...) and total protein and determine purification fold. Great for you would be the first chapters from methods in Enzymology 463 http://www.sciencedirect.com/science/bookseries/00766879/463

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by JackBean
Thu May 09, 2013 2:03 pm
 
Forum: Microbiology
Topic: protein fractionation
Replies: 4
Views: 2064

Re: How did endosymbionts coordinate replication?

... it as an organelle. So, I suppose, in any eukaryotic cell the mtDNA should be relatively conserved. However, the mutational rate of mtDNA is ten fold higher than that of nuclear DNA. So is the mtDNA sequence conserved among e.g. various mammalian species or the opposite?

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by kk
Tue Feb 26, 2013 8:29 am
 
Forum: Cell Biology
Topic: How did endosymbionts coordinate replication?
Replies: 5
Views: 3016

Direct or indirect protein-DNA interaction

... direct interaction with a gene of interest ( we know that the TF has impact on expression because a mutation in the gene coding for it caused a 10-fold decrease in expression of my gene of interest), or if it's a middle step in a series of regulations eventually leading to the gene of interest? ...

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by nukeman
Wed Oct 31, 2012 5:21 pm
 
Forum: Molecular Biology
Topic: Direct or indirect protein-DNA interaction
Replies: 1
Views: 870

How dominance works at the DNA/RNA/protein

... that trait loci can comprise of more than one gene!) You also discover that when that yellow pea color gene produces the same enzyme, but a 1000 fold less of it (say due to a point mutation in the promoter). So, when a plant has at least one copy of the “green” allele it produces 1000 times more ...

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by Cat
Fri Oct 05, 2012 1:15 am
 
Forum: Genetics
Topic: How dominance works at the DNA/RNA/protein
Replies: 10
Views: 5939
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