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Focal adhesion

Focal adhesion

(Science: cell biology) areas of close apposition and thus presumably anchorage points, of the plasma membrane of a fibroblast (for example) to the substratum over which it is moving.

Usually 1m x 0.2 m with the long axis parallel to the direction of movement, always associated with a cytoplasmic microfilament bundle that is attached via several proteins to the plasma membrane at an area of high protein concentration (this is noticeably electron dense in electron micrographs). Focal adhesions tend to be characteristic of slow moving cells.


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Genes and chromosomes II

... tissue and muscle tissus) So if I were looking at genes involved in focal adhesion assembly/disassembly would I have to extract DNA from cells that form focal adhesions? ...

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by LilKim
Thu May 18, 2006 4:15 pm
 
Forum: Molecular Biology
Topic: Genes and chromosomes II
Replies: 14
Views: 6620

Genes and chromosomes II

... mRNA) that I designed my primers against. These genes are involved in focal adhesion and the we are thinking that when one is overexpressed the other should be as well ...

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by curious1
Tue May 16, 2006 10:45 pm
 
Forum: Molecular Biology
Topic: Genes and chromosomes II
Replies: 14
Views: 6620


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