Dictionary » F » Fibroblast

Fibroblast

Definition

noun, plural: fibroblasts

Cell of connective tissue that produces and secretes fibers (e.g. collagens, reticular and elastic fibers) and other ground substance in order to maintain the extracellular matrix (especially during wound healing or tissue repair), and to provide a structural framework for many tissues.


Supplement

They occur in various shapes, such as stellate, fusiform, and spindle-shaped.


Related forms: fibroblastic (adjective).
Related terms: fibroblast growth factors, fibroblast interferon.

See also: collagen.


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Collagen formation by fibroblast

I want to observe and take good pictures of collagen produced by fibroblast (L929) under the microscope. Can anyone help me with the protocol. what can I do to stain collagen and observe them? Thank you...

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by Yeditepe
Thu Oct 06, 2011 4:17 pm
 
Forum: Cell Biology
Topic: Collagen formation by fibroblast
Replies: 1
Views: 3426

Anyone thought about reprogram fibroblast to liver cells?

Maybe can use those core transcriptional regulators that expressed in liver cells? say overexpession of 10 factors together in liver stem cell culture medium?

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by reprogramming
Tue Feb 01, 2011 1:40 pm
 
Forum: Cell Biology
Topic: Anyone thought about reprogram fibroblast to liver cells?
Replies: 1
Views: 1193

Re: cell cloning by limiting dilution

... Friend, As I am awair that you have very good hands-on experience of cell cloning by limiting dilution. I have first time planned to clone mouse fibroblast cells by this method. I need you expert guidance. Please send me the protocol for this. And your critical suggessions. Waiting for your reply. ...

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by anubt22
Mon Sep 06, 2010 5:02 am
 
Forum: Cell Biology
Topic: cell cloning by limiting dilution
Replies: 4
Views: 8734

Limiting dilutions of fibroblast cells

Dear Friends, If anybody have experiance on limiting dilution of adherent cell lines. please explain the detail procedure/protocal. Thanks

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by anubt22
Fri Sep 03, 2010 11:11 am
 
Forum: General Discussion
Topic: Limiting dilutions of fibroblast cells
Replies: 0
Views: 715

help me identify the cells..

how to identify fibroblasts? here are the histology of skin by H&E staining. the 'a' I really think that is fibroblast cell.. but how about the cell by pointing arrows? is it fibroblast also? fibroblast.JPG

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by yaya85
Wed Feb 24, 2010 1:50 pm
 
Forum: Cell Biology
Topic: help me identify the cells..
Replies: 1
Views: 1277
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