Fibrinogen

A mutation was found in intron 1 of the beta fibrinogen gene of a patient suffering afibrogenemia. A construct bearing the mutant of the fibrinogen beta gene was put into COS-7 cells. Using Endo-Porter to deliver a Morpholino into the cultured ...

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... had in our bio lecture was that cells at the site of injury release clotting factors that convert prothrombin to thrombin, which in turn converts fibrinogen to fibrin, which helps platelets to form a clot.

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... The coagulation cascade...the start trigger is tissue damage (or plasma contact with air). I'm a bit hazy on the particulars, but fibrin and fibrinogen come to mind... Try this: http://en.wikipedia.org/wiki/Coagulation

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... thrombokinase ( enzyme ) thrombokinase (2) Prothrombin -------------------> thrombin ( active) (Inactive) Ca2+ ions thrombin (3) Fibrinogen ------------------------> insoluble fibrin threads ( blood clot ) Hope this has helped u :D

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... of globulin. There are other globulin such as alpha- and beta- globulins, while antibody (immunoglobulin) is a gamma-globulin. Plasma = serum + fibrinogen I think that researchers prefer serum than plasma is that because fibrinogen here is not much used for this thing called "crab marking"

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