They may be increased in conditions such as burns, placental abruption, heart disease, DIC, after massive blood transfusion, hypoxia, intrauterine foetal death, portacaval shunt, leukaemia, transfusion reaction, transplant rejection, sepsis, renal failure and preeclampsia.
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... go from glucose to 1,6-fructose-diphosphate; you’re down two molecules of ATP at this point. Aldolase then splits the six-carbon glucose (now 1,6-FDP) into two interconvertible 3-carbon fragments. Now everything doubles-up, so to speak; for each 6 carbon glucose that enters the cycle, 2 three-carbon ...
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