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Fdnb

Fdnb --> fluoro-2,4-dinitrobenzene

a reagent used to combine with the free NH2 group of the NH2-terminal amino acid residue in a peptide, thus marking this residue; the combined forms are known as dnp-proteins, dnp-aminoacyl, etc., the fluorine having been replaced to leave a dinitrophenyl residue (dnp, dnp, or N2Ph-) attached to the NH2 group.

Synonym: Sanger's reagent.

Acronym: fdnb


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